Notre équipe mène un programme de recherche interdisciplinaire pour comprendre la contribution respective des facteurs écologiques, biologiques, socioculturels et anthropologiques dans la régulation de la balance énergétique, du poids et de la santé métabolique. Notre approche combine des modèles et paradigmes uniques dans des environnements extrêmes. En utilisant ces environnements extrêmes, nous cherchons à révéler les mécanismes sous-jacents et à comprendre les déterminants de la régulation du poids et de la santé métabolique. Notre équipe se caractérise par son interdisciplinarité puisque nous mettons en commun notre expertise en physiologie, biologie moléculaire, biologie cellulaire, écologie de la santé, bio-anthropologie, anthropologie culturelle, chimie et physique.
Responsable scientifique : Audrey BERGOUIGNAN
Membres de l’équipe PAGRAS
Publications récentes
↘️ Voir la liste
Bourdier, Pierre; Duboz, Priscilla; Macia, Enguerran; Ka, Abdou; Nazare, Julie-Anne; Cohen, Emmanuel; Boetsch, Gilles; Blanc, Stéphane; Simon, Chantal; Bergouignan, Audrey
How interdisciplinary research at the crossroad between socio-cultural anthropology, and nutritional and physical activity physiology can help addressing the obesity epidemic
Cahiers de nutrition et de diététique, 2021, 56, 51-58. (10.1016/j.cnd.2020.11.003).
Le Roux, Elisa; De Jong, Nathan P.; Blanc, Stéphane; Simon, Chantal; Bessesen, Daniel H.; Bergouignan, Audrey
Physiology of physical inactivity, sedentary behaviors and light physical activity: Insights from space bedrest model
Journal of Physiology (London), 2021, 600, 1037-1051. (10.1113/JP281064).
Le Roux, Elisa; Simon, Chantal; Blanc, Stéphane; Bergouignan, Audrey
Inactivité physique et sédentarité : Impact sur la santé métabolique, de quoi parle-t’on ?
Nutrition & Endocrinologie, 2021, 19(98), 41913. ().
Westerterp, K. R.; Yamada, Y.; Sagayama, H.; Ainslie, P. N.; Andersen, L. F.; Anderson, L. J.; Arab, L.; Baddou, I.; Bedu-Addo, K.; Blaak, E. E.; Blanc, S.; Bonomi, A. G.; Bouten, C. V. C.; Bovet, P.; Buchowski, M. S.; Butte, N. F.; Camps, Sgja; Close, G. L.; Cooper, J. A.; Das, S. K.; Cooper, R.; Dugas, L. R.; Ekelund, U.; Entringer, S.; Forrester, T.; Fudge, B. W.; Goris, A. H.; Gurven, M.; Hambly, C.; El Hamdouchi, A.; Hoos, M. B.; Hu, S.; Joonas, N.; Joosen, A. M.; Katzmarzyk, P.; Kempen, K. P.; Kimura, M.; Kraus, W. E.; Kushner, R. F.; Lambert, E. V.; Leonard, W. R.; Lessan, N.; Martin, C. K.; Medin, A. C.; Meijer, E. P.; Morehen, J. C.; Morton, J. P.; Neuhouser, M. L.; Nicklas, T. A.; Ojiambo, R. M.; Pietilainen, K. H.; Pitsiladis, Y. P.; Plange-Rhule, J.; Plasqui, G.; Prentice, R. L.; Rabinovich, R. A.; Racette, S. B.; Raichlen, D. A.; Ravussin, E.; Reynolds, R. M.; Roberts, S. B.; Schuit, A. J.; Sjodin, A. M.; Stice, E.; Urlacher, S. S.; Valenti, G.; Van Etten, L. M.; Van Mil, E. A.; Wells, J. C. K.; Wilson, G.; Wood, B. M.; Yanovski, J.; Yoshida, T.; Zhang, X.; Murphy-Alford, A. J.; Loechl, C. U.; Luke, A. H.; Pontzer, H.; Rood, J.; Schoeller, D. A.; Wong, W. W.; Speakman, J. R.; International Atomic Energy Agency Doubly Labeled Water database, group
Physical activity and fat-free mass during growth and in later life
American Journal of Clinical Nutrition, 2021, , . (10.1093/ajcn/nqab260).
Speakman, John R.; Yamada, Yosuke; Sagayama, Hiroyuki; Berman, Elena S. F.; Ainslie, Philip N.; Andersen, Lene F.; Anderson, Liam J.; Arab, Lenore; Baddou, Issaad; Bedu-Addo, Kweku; Blaak, Ellen E.; Blanc, Stephane; Bonomi, Alberto G.; Bouten, Carlijn V. C.; Bovet, Pascal; Buchowski, Maciej S.; Butte, Nancy F.; Camps, Stefan G. J. A.; Close, Graeme L.; Cooper, Jamie A.; Creasy, Seth A.; Das, Sai Krupa; Cooper, Richard; Dugas, Lara R.; Ebbeling, Cara B.; Ekelund, Ulf; Entringer, Sonja; Forrester, Terrence; Fudge, Barry W.; Goris, Annelies H.; Gurven, Michael; Hambly, Catherine; El Hamdouchi, Asmaa; Hoos, Marije B.; Hu, Sumei; Joonas, Noorjehan; Joosen, Annemiek M.; Katzmarzyk, Peter; Kempen, Kitty P.; Kimura, Misaka; Kraus, William E.; Kushner, Robert F.; Lambert, Estelle V.; Leonard, William R.; Lessan, Nader; Ludwig, David S.; Martin, Corby K.; Medin, Anine C.; Meijer, Erwin P.; Morehen, James C.; Morton, James P.; Neuhouser, Marian L.; Nicklas, Theresa A.; Ojiambo, Robert M.; Pietiläinen, Kirsi H.; Pitsiladis, Yannis P.; Plange-Rhule, Jacob; Plasqui, Guy; Prentice, Ross L.; Rabinovich, Roberto A.; Racette, Susan B.; Raichlen, David A.; Ravussin, Eric; Reynolds, Rebecca M.; Roberts, Susan B.; Schuit, Albertine J.; Sjödin, Anders M.; Stice, Eric; Urlacher, Samuel S.; Valenti, Giulio; Van Etten, Ludo M.; Van Mil, Edgar A.; Wells, Jonathan C. K.; Wilson, George; Wood, Brian M.; Yanovski, Jack; Yoshida, Tsukasa; Zhang, Xueying; Murphy-Alford, Alexia J.; Loechl, Cornelia U.; Melanson, Edward L.; Luke, Amy H.; Pontzer, Herman; Rood, Jennifer; Schoeller, Dale A.; Westerterp, Klaas R.; Wong, William W.
A standard calculation methodology for human doubly labeled water studies
Cell Reports Medicine, 2021, 2(2), . (10.1016/j.xcrm.2021.100203).
Cussonneau, Laura; Boyer, Christian; Brun, Charlotte; Deval, Christiane; Loizon, Emmanuelle; Meugnier, Emmanuelle; Gueret, Elise; Dubois, Emeric; Taillandier, Daniel; Polge, Cécile; Béchet, Daniel; Gauquelin-Koch, Guillemette; Evans, Alina L.; Arnemo, Jon M.; Swenson, Jon E.; Blanc, Stéphane; Simon, Chantal; Lefai, Etienne; Bertile, Fabrice; Combaret, Lydie
Concurrent BMP Signaling Maintenance and TGF-_ Signaling Inhibition Is a Hallmark of Natural Resistance to Muscle Atrophy in the Hibernating Bear
Cells, 2021, 10(8), 1873. (10.3390/cells10081873).
Careau, V.; Halsey, L. G.; Pontzer, H.; Ainslie, P. N.; Andersen, L. F.; Anderson, L. J.; Arab, L.; Baddou, I.; Bedu-Addo, K.; Blaak, E. E.; Blanc, S.; Bonomi, A. G.; Bouten, C. V. C.; Buchowski, M. S.; Butte, N. F.; Camps, Sgja; Close, G. L.; Cooper, J. A.; Das, S. K.; Cooper, R.; Dugas, L. R.; Eaton, S. D.; Ekelund, U.; Entringer, S.; Forrester, T.; Fudge, B. W.; Goris, A. H.; Gurven, M.; Hambly, C.; El Hamdouchi, A.; Hoos, M. B.; Hu, S.; Joonas, N.; Joosen, A. M.; Katzmarzyk, P.; Kempen, K. P.; Kimura, M.; Kraus, W. E.; Kushner, R. F.; Lambert, E. V.; Leonard, W. R.; Lessan, N.; Martin, C. K.; Medin, A. C.; Meijer, E. P.; Morehen, J. C.; Morton, J. P.; Neuhouser, M. L.; Nicklas, T. A.; Ojiambo, R. M.; Pietilainen, K. H.; Pitsiladis, Y. P.; Plange-Rhule, J.; Plasqui, G.; Prentice, R. L.; Rabinovich, R. A.; Racette, S. B.; Raichlen, D. A.; Ravussin, E.; Reilly, J. J.; Reynolds, R. M.; Roberts, S. B.; Schuit, A. J.; Sjodin, A. M.; Stice, E.; Urlacher, S. S.; Valenti, G.; Van Etten, L. M.; Van Mil, E. A.; Wells, J. C. K.; Wilson, G.; Wood, B. M.; Yanovski, J.; Yoshida, T.; Zhang, X.; Murphy-Alford, A. J.; Loechl, C. U.; Luke, A. H.; Rood, J.; Sagayama, H.; Schoeller, D. A.; Wong, W. W.; Yamada, Y.; Speakman, J. R.; Iaea Dlw database group
Energy compensation and adiposity in humans
Current Biology, 2021, , . (10.1016/j.cub.2021.08.016).
Whipple, M.O.; Regensteiner, J.G.; Bergouignan, Audrey
(Invited Commentary) Is Being Physically Active Enough To Be Metabolically Healthy?: The Key Role of Sedentary Behavior
Diabetes Care, 2021, 44, 17-19. (10.2337/dci20-0064).
Laurens, Claire; Grundler, F.; Damiot, Anthony; Chery, Isabelle; Le Maho, Anne Laure; Zahariev, Alexandre; Le Maho, Yvon; Bergouignan, Audrey; Gauquelin-Koch, Guillemette; Simon, Chantal; Blanc, Stéphane; Wilhelmi de Toledo, Françoise
Is muscle and protein loss relevant in long-term fasting in healthy men? A prospective trial on physiological adaptations
Journal of Cachexia, Sarcopenia and Muscle, 2021, , . (10.1002/jcsm.12766).
Lerch, S.; De La Torre, A.; Huau, C.; Monziols, M.; Xavier, C.; Louis, L.; Le Cozler, Y.; Faverdin, P.; Lamberton, P.; Chery, I.; Heimo, D.; Loncke, C.; Schmidely, P.; Pires, J. A. A.
Estimation of dairy goat body composition: A direct calibration and comparison of eight methods
Methods, 2021, 186, 68-78. (10.1016/j.ymeth.2020.06.014).
Duboz, Priscilla; Macia, Enguerran; Diallo, Amadou H.; Cohen, Emmanuel; Bergouignan, Audrey; Seck, Sidy M.
The good life in rural and urban Senegal: A qualitative and quantitative study
PLOS One, 2021, 16(5), e0252134. (10.1371/journal.pone.0252134).
Herman Pontzer; Yosuke Yamada; Hiroyuki Sagayama; Philip N. Ainslie; Lene F. Andersen; Liam J. Anderson; Lenore Arab; Issaad Baddou; Kweku Bedu-Addo; Ellen E. Blaak; Stephane Blanc; Alberto G. Bonomi; Carlijn V.C. Bouten; Pascal Bovet; Maciej S. Buchowski; Nancy F. Butte; Stefan G. Camps; Graeme L. Close; Jamie A. Cooper; Richard Cooper; Sai Krupa Das; Lara R. Dugas; Ulf Ekelund; Sonja Entringer; Terrence Forrester; Barry W. Fudge; Annelies H Goris; Michael Gurven; Catherine Hambly; Asmaa El Hamdouchi; Marjije B. Hoos; Sumei Hu ; Noorjehan Joonas; Annemiek M. Joosen; Peter Katzmarzyk; Kitty P. Kempen; Misaka Kimura; William E. Kraus; Robert F. Kushner; Estelle V. Lambert; William R. Leonard; Nader Lessan; Corby Martin; Anine C. Medin; Erwin P. Meijer; James C. Morehen; James P. Morton; Marian L. Neuhouser; Theresa A. Nicklas; Robert M. Ojiambo; Kirsi H. Pietiläinen; Yannis P. Pitsiladis; Jacob Plange-Rhule**; Guy Plasqui; Ross L. Prentice; Roberto A. Rabinovich; Susan B. Racette; David A. Raichlen; Eric Ravussin; Rebecca M. Reynolds; Susan B. Roberts; Albertine J. Schuit; Anders M. Sjödin; Eric Stice; Samuel S. Urlacher; Giulio Valenti; Ludo M. Van Etten; Edgar A. Van Mil; Jonathan C. K. Wells; George Wilson; Brian M. Wood; Jack Yanovski; Tsukasa Yoshida; Xueying Zhang; Alexia J. Murphy-Alford; Cornelia Loechl; Amy H Luke; Jennifer Rood; Dale A. Schoeller; Klaas R. Westerterp; William W. Wong; John R. Speakman; IAEA DLW database consortium,
Daily Energy Expenditure through the Human Life Course
Science, 2021, 373, 808-812. (10.1126/science.abe5017).
Simmen, B.; Morino, L.; Blanc, S.; Garcia, C.
The energy allocation trade-offs underlying life history traits in hypometabolic strepsirhines and other primates
Scientific Reports, 2021, 11(1), 14196. (10.1038/s41598-021-93764-x).
Giroud, S.; Chery, I.; Arrive, M.; Prost, M.; Zumsteg, J.; Heintz, D.; Evans, A. L.; Gauquelin-Koch, G.; Arnemo, J. M.; Swenson, J. E.; Lefai, E.; Bertile, F.; Simon, C.; Blanc, S.
Hibernating brown bears are protected against atherogenic dyslipidemia
Scientific Reports, 2021, 11(1), 18723. (10.1038/s41598-021-98085-7).
Guirado, Terry; Metz, Lore; Pereira, Bruno; Bergouignan, Audrey; Thivel, David; Duclos, Martine
Effects of cycling workstation to get tertiary employee moving on their overall health: the REMOVE study
Trials, 2021, 22, . (10.1186/s13063-021-05317-2).
Whipple, M.O.; Masters, K.S.; Huebschmann, A.G.; Scalzo, R.L.; Reusch, J.E.B.; Bergouignan, Audrey; Regensteiner, J.G.
Acute effects of sedentary breaks on vascular health in adults at risk for type 2 diabetes: a systematic review
Vascular Medicine, 2021, 26, 448-458. (10.1177/1358863X211009307).
Boyer, C.; Cussonneau, L.; Brun, C.; Deval, C.; de Barros, J. P. P.; Chanon, S.; Bernoud-Hubac, N.; Daira, P.; Evans, A. L.; Arnemo, J. M.; Swenson, J. E.; Gauquelin-Koch, Guillemette; Simon, Chantal; Blanc, Stéphane; Combaret, L.; Bertile, Fabrice; Lefai, Etienne
Specific shifts in the endocannabinoid system in hibernating brown bears
Frontiers in Zoology, 2020, 17(1), 35. (10.1186/s12983-020-00380-y).
Kenny, Helena C.; Tascher, Georg; Ziemianin, Anna; Rudwill, Floriane; Zahariev, Alexandre; Chery, Isabelle; Gauquelin-Koch, Guillemette; Barielle, Marie-Pierre; Heer, Martina; Blanc, Stéphane; O’Gorman, Donal; Bertile, Fabrice
Effectiveness of resistive vibration exercise and whey protein supplementation plus alkaline salt on the skeletal muscle proteome following 21 days of bedrest in healthy males
Journal of Proteome Research, 2020, 19, 3438-3451. (10.1021/acs.jproteome.0c00256).
Debache, Isaac; Jeantet, Lorène; Chevallier, Damien; Bergouignan, Audrey; Sueur, Cédric
A Lean and Performant Hierarchical Model for Human Activity Recognition Using Body-Mounted Sensors
Sensors, 2020, 20(11), 3090. (10.3390/s20113090).
Thyfault, John P.; Bergouignan, Audrey
Exercise and metabolic health: beyond skeletal muscle
Diabetologia, 2020, , . (10.1007/s00125-020-05177-6).
Laurens, Claire; Bergouignan, Audrey; Moro, Cédric
Exercise-released myokines in the control of energy metabolism. Frontiers in physiology
Frontiers in Physiology, 2020, 11, . (10.3389/fphys.2020.00091).
Arc-Chagnaud, Coralie; Py, Guillaume; Fovet, Théo; Roumanille, Rémi; Demangel, Rémi; Pagano, Allan; Delobel, Pierre; Blanc, Stéphane; Jasmin, Bernard; Blottner, Dieter; Salanova, Michele; Gomez-Cabrera, Mari Carmen; Vina, Jose; Brioche, Thomas; Chopard, Angèle
Evaluation of an antioxidant and anti-inflammatory cocktail against human hypoactivity-induced skeletal muscle deconditioning
Frontiers in Physiology-Environmental, Aviation and Space Physiology, 2020, 11, 71. (10.3389/fphys.2020.00071).
Criscuolo, François; Sueur, Cédric; Bergouignan, Audrey
Human adaptation to deep space environment: an evolutionary perspective of the foreseen interplanetary exploration
Frontiers in Public Health – Environmental Health, 2020, 8, 119. (10.3389/fpubh.2020.00119).
Laurens, Claire; Parmar, Anisha; Murphy, Enda; Carper, Deborah; Lair, Benjamin; Maes, Pauline; Vion, Julie; Boulet, Nathalie; Fontaine, Coralie; Marquès, Marie; Larrouy, Dominique; Harant, Isabelle; Thalamas, Claire; Montastier, Emilie; Caspar-Bauguil, Sylvie; Bourlier, Virginie; Tavernier, Geneviève; Grolleau, Jean-LOs; Bouloumié, Anne; Langin, Dominique; Viguerie, Nathalie; Bertile, Fabrice; Blanc, Stéphane; de Glisezinski, Isabelle; O’Gorman, Donal; Moro, Cedric
Growth and differentiation factor 15 is secreted by skeletal muscle during exercise and promotes lipolysis in humans
JCI Insight, 2020, 5(6), e131870. (10.1172/jci.insight.131870).
Dempsey, Paddy C.; Matthews, Chuck E.; Dashti, S. Ghazaleh; Doherty, Aiden R.; Bergouignan, Audrey; Van Roekel, Eline H.; Dunstan, D. W.; Wareham, Nick J.; Yates, Tom E.; Wijndaele, Katrien; Lynch, Brigid M.
Sedentary behaviour and chronic disease: Mechanisms and future directions
Journal of Physical Activity and Health, 2020, 17, 52-61. (10.1123/jpah.2019-0377).
Halliday, T.M.; Rynders, C. A.; Thomas, E.A.; Bergouignan, Audrey; Pan, Z.; Kealey, E.A.; Cornier, M.A.; Bessesen, D. H.
Appetite-related responses to overfeeding and longitudinal weight change in obesity prone and obesity resistance adults
Obesity, 2020, , . (10.1002/oby.22816).
Thyfault, John P.; Bergouignan, Audrey
Perspective on the article « Fitness and Strength responses to distinct exercise modes in twins: Studies of Twin Responses to understand Exercise as Therapy (STRUETH) study »
The Journal of Physiology, 2020, , . (10.1113/jp280357).
Blanchet, Leslie; Fuchs, Boris; Støen, Ole-Gunnar; Bergouignan, Audrey; Ordiz, Andrés; Laske, Timothy G.; Arnemo, Jon M.; Evans, Alina L.
Movement and heart rate in the Scandinavian brown bear (Ursus arctos)
Animal Biotelemetry, 2019, 7(1), 18. (10.1186/s40317-019-0181-7).
Chazarin, Blandine; Ziemianin, Anna; Evans, Alina L.; Meugnier, Emmanuelle; Loizon, Emmanuelle; Chery, Isabelle; Arnemo, Jon M.; Swenson, Jon E.; Gauquelin-Koch, Guillemette; Simon, Chantal; Blanc, Stéphane; Lefai, Etienne; Bertile, Fabrice
Limited Oxidative Stress Favors Resistance to Skeletal Muscle Atrophy in Hibernating Brown Bears (Ursus Arctos)
Antioxidants, 2019, 8(9), 334. (10.3390/antiox8090334).
Chazarin, Blandine; Storey, Kenneth B.; Ziemianin, Anna; Chanon, Stéphanie; Plumel, Marine; Chery, Isabelle; Durand, Christine; Evans, Alina L.; Arnemo, Jon M.; Zedrosser, Andreas; Swenson, Jon E.; Gauquelin-Koch, Guillemette; Simon, Chantal; Blanc, Stéphane; Lefai, Etienne; Bertile, Fabrice
Metabolic reprogramming involving glycolysis in the hibernating brown bear skeletal muscle
Frontiers in Zoology, 2019, 16, 12. (10.1186/s12983-019-0312-2).
Kletty, F.; Tissier, M.; Kourkgy, C.; Capber, F.; Zahariev, A.; Chatelain, N.; Courtecuisse, J.; Le Maho, Y.; Habold, C.
A focus on the European hamster to illustrate how to monitor endangered species
Integrative Zoology, 2019, 14(1), 65-74. (10.1111/1749-4877.12375).
Debache, Isaac; Bergouignan, Audrey; Chaix, Basile; Sneekes, E. M.; Thomas, F.; Sueur, Cédric
Associations of Sensor-Derived Physical Behavior with Metabolic Health: A Compositional Analysis in the Record Multisensor Study
International Journal of Environmental Research and Public Health, 2019, 16(5), 15. (10.3390/ijerph16050741).
Damiot, Anthony; Demangel, Rémi; Noone, John; Chery, Isabelle; Zahariev, Alexandre; Normand, Sylvie; Brioche, Thomas; Crampes, François; Deglisezinski, Isabelle; Lefai, Etienne; Bareille, Marie-Pierre; Chopard, Angèle; Drai, Jocelyne; Collin-Chavagnac, Delphine; Heer, Martina; Gauquelin-Koch, Guillemette; Prost, Michel; Simon, Patrick; Py, Guillaume; Blanc, Stéphane; Simon, Chantal; Bergouignan, Audrey; O’Gorman, Donal
A nutrient cocktail prevents lipid metabolism alterations induced by 20 days of daily steps reduction and fructose overfeeding: Result from a randomized study
Journal of Applied Physiology, 2019, 126(1), 88-101. (10.1152/japplphysiol.00018.2018).
De Jong, Nathan P.; Rynders, C. A.; Goldstrohm, D. A.; Pan, Z.; Lange, A. H.; Mendez, C.; Melanson, E. L.; Bessesen, D. H.; Bergouignan, Audrey
Effect of frequent interruptions of sedentary time on nutrient metabolism in sedentary overweight male and female adults
Journal of Applied Physiology, 2019, 126(4), 984-992. (10.1152/japplphysiol.00632.2018).
Rimbach, R.; Blanc, Stéphane; Zahariev, Alexandre; Pillay, N.; Schradin, Carsten
Daily energy expenditure of males following alternative reproductive tactics: Solitary roamers spend more energy than group-living males
Physiology & Behavior, 2019, 199, . (10.1016/j.physbeh.2018.12.003).
Roth, Jeffrey D.; Dobson, F. Stephen; Criscuolo, Francois; Uhlrich, Pierre; Zahariev, Alexandre; Bergouignan, Audrey; Viblanc, Vincent A.
Subtle short-term physiological costs of an experimental augmentation of fleas in wild Columbian ground squirrels
The Journal of Experimental Biology, 2019, 222(12), UNSP jeb203588. (10.1242/jeb.203588).
Rimbach, Rebecca; Blanc, Stéphane; Zahariev, Alexandre; Robin, Jean-Patrice; Pillay, Neville; Schradin, Carsten
Fat content of striped mice decreases during the breeding season but not during the food-restricted dry season
The Journal of Experimental Biology, 2019, 222(24), jeb208504. (10.1242/jeb.208504).
Pifferi, Fabien; Terrien, Jérémy; Perret, Martine; Epelbaum, Jacques; Blanc, Stéphane; Picq, Jean-Luc; Dhenain, Marc; Aujard, Fabienne
Promoting healthspan and lifespan with caloric restriction in primates
Communications Biology, 2019, 2(1), 107. (10.1038/s42003-019-0348-z).
Laurens, Claire; Simon, Chantal; Vernikos, Joan; Gauquelin-Koch, Guillemette; Blanc, Stéphane; Bergouignan, Audrey
Revisiting the role of exercise countermeasure on the regulation of energy balance during space flight
Frontiers in Physiology, 2019, 10, 321. (10.3389/fphys.2019.00321).
Giroud, Sylvain; Chery, Isabelle; Bertile, Fabrice; Bertrand-Michel, Justine; Tascher, Georg; Gauquelin-Koch, Guillemette; Arnemo, Jon M.; Swenson, Jon E.; Singh, Navinder J.; Lefai, Etienne; Evans, Aline L.; Simon, Chantal; Blanc, Stéphane
Lipidomics Reveals Seasonal Shifts in a Large-Bodied Hibernator, the Brown Bear
Frontiers in Physiology, 2019, 10, 389. (10.3389/fphys.2019.00389).
Arevström, Lilith; Bergh, Cecilia; Landberg, Rikard; Wu, Huaxing; Rodriguez-Mateos, Ana; Waldenborg, Micael; Magnuson, Anders; Blanc, Stepháne; Fröbert, Ole
Freeze-dried bilberry (Vaccinium myrtillus) dietary supplement improves walking distance and lipids after myocardial infarction: an open-label randomized clinical trial
Nutrition Research, 2019, 62, 13-22. (10.1016/j.nutres.2018.11.008).
Ostendorf, D.; Caldwell, A.E.; Creasy, S.A.; Pan, Z.; Lyden, K.; Bergouignan, Audrey; MacLean, P. S.; Wyatt, H.R.; Hill, J. O.; Melanson, E. L.; Catenacci, V.A.
Physical activity energy expenditure and total daily energy expenditure in successful weight loss maintainers
Obesity, 2019, 27(3), 496-504. (10.1002/oby.22373).
Wilhelmi de Toledo, Françoise; Grundler, F.; Bergouignan, Audrey; Drinda, S.; Michalsen, A.
Safety, health improvement and well-being during a 4 to 21-day fasting period in an observational study including 1422 subjects
PLOS One, 2019, 14(1), e0209353. (10.1371/journal.pone.0209353).
Grace, M. S.; Formosa, M. F.; Bozaoglu, K.; Bergouignan, A.; Brozynska, M.; Carey, A. L.; Veiga, C. B.; Sethi, P.; Dillon, F.; Bertovic, D. A.; Inouye, M.; Owen, N.; Dunstan, D. W.; Kingwell, B. A.
Acute effects of active breaks during prolonged sitting on subcutaneous adipose tissue gene expression: an ancillary analysis of a randomised controlled trial
Scientific Reports, 2019, 9, . (10.1038/s41598-019-40490-0).
De Jong, N. P.; Debache, Isaac; Pan, Z. X.; Garnotel, M.; Lyden, K.; Sueur, Cédric; Simon, Chantal; Bessesen, D. H.; Bergouignan, Audrey
Breaking up Sedentary Time in Overweight/Obese Adults on Work Days and Non-Work Days: Results from a Feasibility Study
International Journal of Environmental Research and Public Health, 2018, 15(11), 2566. (10.3390/ijerph15112566).
Garnotel, M.; Bastian, T.; Romero-Ugalde, H. M.; Maire, A.; Dugas, J.; Zahariev, Alexandre; Doron, M.; Jallon, P.; Charpentier, G.; Franc, S.; Blanc, Stéphane; Bonnet, S.; Simon, Chantal
Prior automatic posture and activity identification improves physical activity energy expenditure prediction from hip-worn triaxial accelerometry
Journal of Applied Physiology, 2018, 124(3), 780-790. (10.1152/japplphysiol.00556.2017).
Rudwill, Floriane; O’Gorman, Donal; Lefai, Etienne; Chery, Isabelle; Zahariev, Alexandre; Normand, Sylvie; Damiot, Anthony; Laurens, Claire; Hodson, Leanne; Canet-Soulas, Emmanuelle; Heer, Martina; Frings-Meuthen, Petra; Buehlmeier, Judith; Baecker, Natalie; Meiller, Laure; Gauquelin-Koch, Guillemette; Blanc, Stéphane; Simon, Chantal; Bergouignan, Audrey
Metabolic inflexibility is an early marker of muscle insulin resistance induced by 21 days of bed rest even when fat mass is stable
Journal of Clinical Endocrinology and Metabolism, 2018, 103, 1910-1920. (10.1210/jc.2017-02267).
Rimbach, Rebecca; Blanc, Stéphane; Zahariev, Alexandre; Gatta, Maria; Pillay, Neville; Schradin, Carsten
Seasonal variation in energy expenditure in a rodent inhabiting a winter-rainfall desert
Journal of Comparative Physiology B, 2018, 188(5), 877-888. (10.1007/s00360-018-1168-z).
Pifferi, Fabien; Terrien, Jérémy; Marchal, Julia; Dal-Pan, Alexandre; Djelti, Fathia; Hardy, Isabelle; Chahory, Sabine; Cordonnier, Nathalie; Desquilbet, LoIc; Hurion, Murielle; Zahariev, Alexandre; Chery, Isabelle; Zizzari, Philippe; Perret, Martine; Epelbaum, Jacques; Blanc, Stéphane; Picq, Jean Luc; Dhenain, Marc; Aujard, Fabienne
Caloric restriction increases lifespan but affects brain integrity in grey mouse lemur primates
Communications Biology, 2018, , 30. (10.1038/s42003-018-0024-8).
Mahlert, Britta; Gerritsmann, Hanno; Stalder, Gabrielle; Ruf, Thomas; Zahariev, Alexandre; Blanc, Stéphane; Giroud, Sylvain
Implications of being born late in the active season for growth, fattening, torpor use, winter survival and fecundity
eLife, 2018, , e31225. (10.7554/eLife.31225).
Rynders, Corey A.; Blanc, Stéphane; DeJong, Nathan; Bessesen, Daniel H.; Bergouignan, Audrey
Sedentary behaviour is a key determinant of metabolic inflexibility
Journal of Physiology-London, 2018, 596(8), 1319-1330. (10.1113/JP273282).
Sha, J. C. M.; Kurihara, Y.; Tsuji, Y.; Take, M.; He, T.; Kaneko, A.; Suda-Hashimoto, N.; Morimoto, M.; Natsume, T.; Zahariev, A.; Blanc, Stéphane; Hanya, G.
Seasonal variation of energy expenditure in Japanese macaques (Macaca fuscata)
Journal of Thermal Biology, 2018, 76, 139-146. (10.1016/j.jtherbio.2018.07.009).
Creasy, S.A.; Rynders, C.A.; Bergouignan, Audrey; Kealey, E.; Bessesen, D.H.
Free-living responses in energy balance to short-term overfeeding in adults differing in propensity for obesity
Obesity, 2018, 26(4), 696-702. (10.1002/oby.22121).
Rynders, C.A.; Pereira, R.; Bergouignan, Audrey; Kealey, E.; Bessesen, D.H.
Associations among dietary fat oxidation responses to overfeeding and weight gain in obesity-prone and resistant adults
Obesity, 2018, 26(11), 1758-1766. (10.1002/oby.22321).
Rynders, C.A.; Schmidt, S.L.; Bergouignan, Audrey; Horton, T.J.; Bessesen, D.H.
Effects of short-term sex steroid suppression on dietary fat storage patterns in healthy males
Physiological Reports, 2018, 6, e13533. (10.14814/phy2.13533).
Foright, R. M.; Presby, D. M.; Sherk, V. D.; Kahn, D.; Checkley, L. A.; Giles, E. D.; Bergouignan, A.; Higgins, J. A.; Jackman, M. R.; Hill, J. O.; MacLean, P. S.
Is regular exercise an effective strategy for weight loss maintenance?
Physiology & Behavior, 2018, 188, 86-93. (10.1016/j.physbeh.2018.01.025).
Arinell, Karin; Blanc, Stéphane; Welinder, K. G.; Støen, O. G.; Evans, A. L.; Fröbert, O.
Physical inactivity and platelet function in humans and brown bears: A comparative study
Platelets, 2018, 29, 87-90. (10.1080/09537104.2017.1336530).
Giroud, Sylvain; Evans, Alina; Isabelle, Chery; Bertile, Fabrice; Tascher, Georg; Bertrand-Michel, Justine; Gauquelin-Koch, Guillemette; Arnemo, Jon; Swenson, Jon; Lefai, Etienne; Blanc, Stéphane; Simon, Chantal
Seasonal changes in eicosanoid metabolism in the brown bear
Science of Nature, 2018, 105(9-10), 58. (10.1007/s00114-018-1583-8).
Chanon, Stéphanie; Chazarin, Blandine; Toubhans, Benoit; Durand, Christine; Chery, Isabelle; Robert, Maud; Vieille-Marchiset, Aurélie; Swenson, Jon E.; Zedrosser, Andreas; Evans, A. L.; Brunberg, Sven; Arnemo, Jon M.; Gauquelin-Koch, Guillemette; Storey, Kenneth B.; Simon, Chantal; Blanc, Stéphane; Bertile, Fabrice; Lefai, Etienne
Proteolysis inhibition by winter bear serum leads to increased protein content in human muscle cells
Scientific Reports, 2018, 8, 5525. (10.1038/s41598-018-23891-5).
Chambault, Philippine; Giraudou, Lucie; de Thoisy, Benoît; Bonola, Marc; Kelle, Laurent; Dos Reis, Virginie; Blanchard, Fabian; Le Maho, Yvon; Chevallier, Damien
Habitat use and diving behaviour of gravid olive ridley sea turtles under riverine conditions in French Guiana
Journal of Marine Systems, 2017, 165, 115-123. (10.1016/j.jmarsys.2016.10.005).
Tascher, Georg; Brioche, Thomas; Maes, Pauline; Chopard, Angèle; O’Gorman, Donal; Gauquelin-Koch, Guillemette; Blanc, Stéphane; Bertile, Fabrice
Proteome-wide adaptations of mouse skeletal muscles during a full month in space
Journal of Proteome Research, 2017, 16(7), 2623-2638. (10.1021/acs.jproteome.7b00201).
Treffel, Loic; Massabuau, Nicolas; Zuj, K.; Custaud, M. A.; Gauquelin-Koch, Guillemette; Blanc, Stéphane; Gharib, C.; Millet, C.
Pain and Vertebral Dysfunction in Dry Immersion: A Model of Microgravity Simulation Different from Bed Rest Studies
Pain Research & Management, 2017, , ID9602131. (10.1155/2017/9602131).
Bize, Pierre; Daniel, G.; Viblanc, Vincent; Martin, J.; Doligez, B.
Negative phenotypic and genetic correlation between natal dispersal propensity and nest defence behaviour in a wild bird
Biology Letters, 2017, 13(7), 20170236. (10.1098/rsbl.2017.0236).
Kenny, Helena C.; Rudwill, Floriane; Breen, Laura; Salanova, Michele; Blottner, Dieter; Heise, Tim; Heer, Martina; Blanc, Stephane; O’Gorman, Donal J.
Bed rest and resistive vibration exercise unveil novel links between skeletal muscle mitochondrial function and insulin resistance
Diabetologia, 2017, 60(8), 14791-1501. (10.1007/s00125-017-4298-z).
Lefai, Etienne; Blanc, Stéphane; Momken, Iman; Antoun, Edwina; Chery, Isabelle; Zahariev, Alexandre; Gabert, Laure; Bergouignan, Audrey; Simon, Chantal
Exercise training improves fat metabolism independent of total energy expenditure in sedentary overweight men, but does not restore lean metabolic phenotype
International Journal of Obesity, 2017, 41(12), 1728-1736. (10.1038/ijo.2017.151).
Stumpfel, Stefan; Bieber, Claudia; Blanc, Stéphane; Ruf, Thomas; Giroud, Sylvain
Differences in growth rates and pre-hibernation body mass gain between early and late-born juvenile garden dormice
Journal of comparative physiology B-biochemical systemic and environmental physiology, 2017, 187, 253. (10.1007/s00360-016-1017-x).
Evans, Alina L.; Singh, Navinder J.; Fuchs, Boris; Blanc, Stéphane; Friebe, Andrea; Laske, Timothy G.; Frobert, Ole; Swenson, Jon E.; Arnemo, Jon M.
Physiological reactions to capture in hibernating brown bears
Conservation Physiology, 2016, 4, cow061. (10.1093/conphys/cow061).
Saraux, Claire; Chiaradia, A; Salton, M.; Dann, P.; Viblanc, Vincent A.
Negative effects of wind speed on individual foraging performance and breeding success in little penguins
Ecological Monographs, 2016, 86, 61-77. (10.1890/14-2124.1).
Treffel, Loïc; Mkhitaryan, Karen; Gellee, Stéphane; Gauquelin-Koch, Guillemette; Gharib, Claude; Blanc, Stéphane; Millet, Catherine
Intervertebral disc swelling demonstrated by 3D and water content magnetic resonance analyses after a 3-day dry immersion simulating microgravity
Frontiers in Physiology, 2016, 7(605), . (10.3389/fphys.2016.00605).
Evans, Alina L.; Singh, Navinder; Freibe, Andrea; Arnemo, Jon M.; Laske, Tim G.; Fröbert, Ole; Swenson, Jon E.; Blanc, Stéphane
Drivers of hibernation in the brown bear
Frontiers in Zoology, 2016, 13, 7. (10.1186/s12983-016-0140-6).
Treffel, Loic; Dmitrieva, Liubov; Gauquelin-Koch, Guillemette; Custaud, Marc-Antoine; Blanc, Stephane; Gharib, Claude; Millet, Catherine
Craniomandibular System and Postural Balance after 3-Day Dry Immersion
PLOS One, 2016, 11(2), e010052. (10.1371/journal.pone.0150052).
Récapet, Charlotte; Zahariev, Alexandre; Blanc, Stéphane; Arrivé, Mathilde; Criscuolo, François; Bize, Pierre; Doligez, Blandine
Differences in the oxidative balance of dispersing and non-dispersing individuals: an experimental approach in a passerine bird
BMC Evolutionary Biology, 2016, 16, 125. (10.1186/s12862-016-0697-x).
Gastebois, Caroline; Villars, Clément; Drai, Jocelyne; Canet-Soulas, Emmanuelle; Blanc, Stéphane; Bergouignan, Audrey; Lefai, Etienne; Simon, Chantal
Effects of training and detraining on adiponectin plasma concentration and muscle sensitivity in lean and overweight men
European Journal of Applied Physiology, 2016, 116(11-12), 2135-2144. (10.1007/s00421-016-3466-z).
Bergouignan, Audrey; Legget, Kristina T.; De Jong, Nathan; Kealey, Elizabeth; Nikolovski, Janet; Groppel, Jack L.; Jordan, Chris; O’Day, Raphaela; Hill, James O.; Bessesen, Daniel H.
Effect of frequent interruptions of prolonged sitting on self-perceived levels of energy, mood, food cravings and cognitive function
International Journal of Behavioral Nutrition and Physical Activity, 2016, 13(1), 113. (10.1186/s12966-016-0437-z).
White, Olivier; Clément, Gilles; Fortrat, Jacques-Olivier; Pavy-LeTraon, Anne; Thonnard, Jean-Louis; Blanc, Stéphane; Wuyts, Floris L.; Paloski, William H.
Towards human exploration of space: the THESEUS review series on neurophysiology research priorities
NPJ Microgravity, 2016, 2, 16023. (10.1038/npjmgrav.2016.23).
Aubert, André E.; Larina, Irina; Momken, Iman; Blanc, Stéphane; White, Olivier; Prisk, Kim; Linnarsson, Dag
Towards Human Exploration of Space: The THESEUS review series on cardiovascular, respiratory, and renal research priorities
NPJ Microgravity, 2016, 2, 16031. (10.1038/npjmgrav.2016.31).
Vernikos, Joan; Walter, Nicolas; Worms, Jean Claude; Blanc, Stéphane
THESEUS: The European research priorities for human exploration of space
NPJ Microgravity, 2016, 2, 16034. (10.1038/npjmgrav.2016.34).
Bergouignan, Audrey; Stein, Peter; Habold, Caroline; Coxam, Véronique; O’Gorman, Donal; Blanc, Stéphane
Towards Human Exploration of Space: The THESEUS review series on nutrition and metabolism research priorities
NPJ Microgravity, 2016, 2, 16029. (10.1038/npjmgrav.2016.29).
Gastebois, Caroline; Chanon, Stéphanie; Rome, Sophie; Durand, Christine; Pelascini, Elise; Jalabert, Audrey; Euthine, Vanessa; Pialoux, Vincent; Blanc, Stéphane; Simon, Chantal; Lefai, Etienne
Transition from physical activity to inactivity increases skeletal muscle miR_148b content and triggers insulin resistance
Physiological Reports, 2016, 4, e12902. (10.14814/phy2.12902).
Dali-Youcef, Nassim; Hnia, Karim; Blaise, Sebastien; Messaddeq, Nadia; Blanc, Stéphane; Postic, Catherine; Valet, Philippe; Tomasetto, Catherine; Rio, Marie-Christine
Matrix metalloproteinase 11 protects from diabesity and promotes metabolic switch
Scientific Reports, 2016, 6, 25140. (10.1038/srep25140).
Bergouignan, Audrey; Latouche, Celine; Heywood, Sarah; Grace, Megan; Reddy-Luthmoodoo, Medini; Natoli, Alaina; Owen, Neville; Dunstan, David; Kingwell, Bronwyn
Frequent interruptions of sedentary time modulates contraction- and insulin-stimulated glucose uptake pathways in muscle: Ancillary analysis from randomized clinical trials
Scientific Reports, 2016, 6, 32044. (10.1038/srep32044).