BioOrganic Mass Spectrometry laboratory – LSMBO

The BioOrganic Mass Spectrometry laboratory (LSMBO) belongs to the Institut Plurisciplinaire Hubert Curien (IPHC : http://www.iphc.cnrs.fr/) of the University of Strasbourg. The LSMBO is hosting an IBiSA-certified proteomic platform (Strasbourg Grand Est Proteomic Platform) and is the Strasbourg node of the French Proteomic Infrastructure (ProFI). The LSMBO is a 30 year-experienced team in the structural study of peptides and proteins by mass spectrometry. The laboratory is renowned for developing new methods in proteomic analysis, bioinformatics and structural mass spectrometry for the analysis of protein/protein interactions in large complexes. Besides that, long term collaborations with several pharmaceutical companies cover topics such as full characterization of natural and/or recombinant proteins used in human therapy, toxicoproteomics, protein/drug interaction.
The LSMBO team develops innovative methodologies in chromatography, mass spectrometry (MS) and bioinformatics for :

  • Functional proteomic analysis for the identification and quantification of thousands of proteins in complex biological matrices (sample preparation, targeted (PRM) and global (DIA) quantitative LC-MS/MS analysis, statistical analysis and integration of multi-omics data).
  • Structural proteomic analysis for the characterization of either proteins alone or in complexes. The combination of native MS, mass photometry, ion mobility, H/D exchange and chemical cross-linking approaches followed by MS is applied to integrative structural biology projects.
  • Characterization of therapeutic proteins (monoclonal antibodies).
  • Interpretation of functional (Proline) and structural proteomic data.

The LSMBO hosts the Strasbourg Grand Est proteomics platform (PSGE) and is the Strasbourg node of the national Proteomics Infrastructure ProFI. The LSMBO is a partner of two TIT programs of the University of Strasbourg, IMS and TransplantexNG.

Scientifique coordinators: Sarah CIANFERANI, Christine CARAPITO

LSMBO Team members


Fabrice BERTILE

Chercheur
Go to card

Adrien BROWN

IT
Go to card

Léo-Paul BRUNEL

Stagiaire
Go to card

Alexandre BUREL

IT
Go to card

Christine CARAPITO

Chercheur
Go to card

Sarah CIANFERANI

Chercheur
Go to card

Dinu Zinovie CIOBANU

Chercheur
Go to card

Noelia DE LAMA VALDERRAMA

Doctorant
Go to card

François DELALANDE

IT
Go to card

Sarah DELAUX

Doctorant
Go to card

Véronique DELVAL DUBOIS

Enseigant-chercheur
Go to card

Hélène DIEMER

IT
Go to card

Hugo EICHHORN

IT
Go to card

Stéphane ERB

IT
Go to card

Valériane GAXOTTE

IT
Go to card

Alexandre GEFFROY

Doctorant
Go to card

Hugo GIZARDIN-FREDON

Doctorant
Go to card

Oscar HERNANDEZ ALBA

Chercheur
Go to card

Chawin HOERNEL

Doctorant
Go to card

Agnès HOVASSE

IT
Go to card

Shabnam HUSEYNOVA

IT
Go to card

Mathilde KEHRWILLER

Apprenti
Go to card

Sunu LAMA

Chercheur
Go to card

Léa LETISSIER

Doctorant
Go to card

Lucie MAZZUCOTELLI

Doctorant
Go to card

Reiko NAKAO

Enseigant-chercheur
Go to card

Sarah NGUYEN

Doctorant
Go to card

Pauline PERDU-ALLOY

Doctorant
Go to card

Jeewan Babu RIJAL

IT
Go to card

Martine RIVET

IT
Go to card

Magali ROMPAIS

IT
Go to card

Laurence SABATIER

Enseigant-chercheur
Go to card

Farida SALIMOVA

Doctorant
Go to card

Christine SCHAEFFER

IT
Go to card

Jean Marc STRUB

IT
Go to card

Guillaume TRAORE

IT
Go to card

Fabrice VARRIER

IT
Go to card

Olivier VERHOEV

Chercheur
Go to card

Publications