Spectrométrie de masse bioorganique – LSMBO

L’équipe LSMBO développe des méthodologies innovantes en chromatographie, spectrométrie de masse (MS) et bioinformatique pour :

  • L’analyse protéomique fonctionnelle pour l’identification et la quantification de milliers de protéines dans des matrices biologiques complexes (préparation d’échantillon, analyse LC-MS/MS quantitative ciblée (PRM) et globale (DIA), analyse statistique et intégration de données multi-omiques).
  • L’analyse protéomique structurale pour la caractérisation de protéines seules ou en  complexes. La combinaison d’approches de MS native, photométrie de masse, mobilité ionique, échange H/D et pontage chimique suivis par MS complète ainsi les approches de biologie structurale intégrative. 
  • La caractérisation de protéines thérapeutiques (anticorps monoclonaux).
  • L’interprétation des données de protéomique fonctionnelle (Proline) et structurale.

Le LSMBO héberge la plateforme protéomique Strasbourg Grand Est (PSGE) et le site Strasbourg de l’Infrastructure nationale de Protéomique ProFI. Le LSMBO est partenaire des ITI IMS et TransplantexNG.

Responsables scientifiques : Sarah CIANFERANI, Christine CARAPITO

Membres de l’équipe LSMBO


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Adrien BROWN

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Alexandre BUREL

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Christine CARAPITO

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Stéphane ERB

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Valériane GAXOTTE

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Alexandre GEFFROY

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Jeewan Babu RIJAL

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Martine RIVET

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Jean Marc STRUB

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Guillaume TRAORE

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Publications récentes

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C. Mons, M. Salameh, T. Botzanowski, M. Clemancey, P. Dorlet, C. Vallieres, S. Erb, L. Vernis, O. Guittet, M. Lepoivre, M. E. Huang, S. Cianferani, J. M. Latour, G. Blondin and M. P. Golinelli-Cohen
Regulations of mitoNEET by the key redox homeostasis molecule glutathione
J Inorg Biochem, 2024, 255, 112535. (10.1016/j.jinorgbio.2024.112535)

T. Rady, S. Erb, S. Deddouche-Grass, R. Morales, G. Chaubet, S. Cianférani, N. Basse and A. Wagner
Targeted delivery of immune-stimulating bispecific RNA, inducing apoptosis and anti-tumor immunity in cancer cells
Iscience, 2024, 27, ARTN 109068 (10.1016/j.isci.2024.109068)

E. Partiot, A. Hirschler, S. Colomb, W. Lutz, T. Claeys, F. Delalande, M. S. Deffieu, Y. Bare, J. R. E. Roels, B. Gorda, J. Bons, D. Callon, L. Andreoletti, M. Labrousse, F. M. J. Jacobs, V. Rigau, B. Charlot, L. Martens, C. Carapito, G. Ganesh and R. Gaudin
Brain exposure to SARS-CoV-2 virions perturbs synaptic homeostasis
Nature Microbiology, 2024, (10.1038/s41564-024-01657-2)

D. Gomez-Zepeda, D. Arnold-Schild, J. Beyrle, A. Declercq, R. Gabriels, E. Kumm, A. Preikschat, M. K. Lacki, A. Hirschler, J. B. Rijal, C. Carapito, L. Martens, U. Distler, H. Schild and S. Tenzer
Thunder-DDA-PASEF enables high-coverage immunopeptidomics and is boosted by MS(2)Rescore with MS(2)PIP timsTOF fragmentation prediction model
Nat Commun, 2024, 15, 2288. (10.1038/s41467-024-46380-y)

N. Del Giudice, G. Voegeli, J. M. Strub, B. Heinrich and L. Douce
Ionic Liquid Crystals Based on Loop-Shaped Copper(I) Complexes
Inorg Chem, 2024, 63, 6103-6110. (10.1021/acs.inorgchem.4c00728)

R. Benazza, I. Koutsopetras, V. Vaur, G. Chaubet, O. H.-. Alba and S. Cianferani
SEC-MS in denaturing conditions (dSEC-MS) for in-depth analysis of rebridged monoclonal antibody-based formats
Talanta, 2024, 272, ARTN 125727 (10.1016/j.talanta.2024.125727)

N. Becharguia, I. Nierengarten, J. M. Strub, S. Cianférani, M. Rémy, E. Wasielewski, R. Abidi and J. F. Nierengarten
Solution and Solvent-Free Stopper Exchange Reactions for the Preparation of Pillar[5]arene-containing [2] and [3]Rotaxanes
Chemistry-a European Journal, 2024, 30, (10.1002/chem.202304131)

A. Beauvieux, B. Mérigot, J. Le Luyer, J. M. Fromentin, N. Couffin, A. Brown, O. Bianchimani, R. Hocdé, D. Aurelle, J. B. Ledoux, F. Bertile and Q. Schull
Mesophotic zone as refuge: acclimation and in-depth proteomic response of yellow gorgonians in the Mediterranean sea
Coral Reefs, 2024, (10.1007/s00338-024-02477-w)

A. Beauvieux, J. M. Fromentin, D. Romero, N. Couffin, A. Brown, L. Metral, J. Bourjea, F. Bertile and Q. Schull
Molecular fingerprint of gilthead seabream physiology in response to pollutant mixtures in the wild
Environ Pollut, 2024, 340, 122789. (10.1016/j.envpol.2023.122789)

I. Shajan, L. N. C. Rochet, S. R. Tracey, B. Jackowska, R. Benazza, O. Hernandez-Alba, S. Cianférani, C. J. Scott, F. L. van Delft, V. Chudasama and B. Albada
Rapid Access to Potent Bispecific T Cell Engagers Using Biogenic Tyrosine Click Chemistry
Bioconjugate Chemistry, 2023, 34, 2215-2220. (10.1021/acs.bioconjchem.3c00357)

V. Lehot, O. Lidicky, J. Most, S. Erb, I. Dovgan, A. Osypenko, O. Koniev, S. Kolodych, L. Kotrchova, G. Chaubet, S. Cianferani, T. Etrych and A. Wagner
Reinvestigation of the Automated Synthesis of Stoichiometrically Conjugated Antibodies to Access High Molecular Weight Payloads and Multiplexed Conjugation via an In-Solution Trans-Tagging Process
Acs Omega, 2023, 8, 40508-40516. (10.1021/acsomega.3c05206)

I. Koutsopetras, V. Vaur, R. Benazza, H. Diemer, C. Sornay, Y. Ersoy, L. Rochet, C. Longo, O. Hernandez-Alba, S. Erb, A. Detappe, A. Skerra, A. Wagner, S. Cianferani and G. Chaubet
Site-Selective Protein Conjugation by a Multicomponent Ugi Reaction
Chemistry, 2023, e202303242. (10.1002/chem.202303242)

T. Grea, G. Jacquot, A. Durand, C. Mathieu, A. Gasser, C. Zhu, M. Banerjee, E. Hucteau, J. Mallard, P. L. Navarro, B. V. Popescu, E. Thomas, D. Kryza, J. Sidi-Boumedine, G. Ferrauto, E. Gianolio, G. Fleith, J. Combet, S. Brun, S. Erb, S. Cianferani, L. J. Charbonnière, L. Fellmann, C. Mirjolet, L. David, O. Tillement, F. Lux, S. Harlepp, X. Pivot and A. Detappe
Subcutaneous Administration of a Zwitterionic Chitosan-Based Hydrogel for Controlled Spatiotemporal Release of Monoclonal Antibodies
Advanced Materials, 2023, (10.1002/adma.202308738)

N. Demeulemeester, M. Gebelin, L. Caldi Gomes, P. Lingor, C. Carapito, L. Martens and L. Clement
msqrob2PTM: differential abundance and differential usage analysis of MS-based proteomics data at the post-translational modification and peptidoform level
Mol Cell Proteomics, 2023, 100708. (10.1016/j.mcpro.2023.100708)

P. Coliat, S. Erb, H. Diemer, D. Karouby, T. Martin, M. Banerjee, C. Zhu, M. Demarchi, S. Cianferani, A. Detappe and X. Pivot
Influence of pneumatic transportation on the stability of monoclonal antibodies
Sci Rep, 2023, 13, 21875. (10.1038/s41598-023-49235-6)

C. Beaumal, E. Deslignière, H. Diemer, C. Carapito, S. Cianfréani and O. Hernandez-Alba
Improved characterization of trastuzumab deruxtecan with PTCR and internal fragments implemented in middle-down MS workflows
Analytical and Bioanalytical Chemistry, 2023, (10.1007/s00216-023-05059-x)

N. Trometer, B. Cichocki, Q. Chevalier, J. Pécourneau, J. M. Strub, A. Hemmerlin, A. Specht, E. Davioud-Charvet and M. Elhabiri
Synthesis and Photochemical Properties of Fluorescent Metabolites Generated from Fluorinated Benzoylmenadiones in Living Cells
Journal of Organic Chemistry, 2023, 89, 2104-2126. (10.1021/acs.joc.3c00620)

F. Arsène-Ploetze, M. Rompais, A. Alioua, V. Cognat, M. Erhardt, S. Graindorge, S. Koechler, J. Mutterer, C. Carapito and H. Schaller
Streptomyces cocklensis DSM 42063 and Actinacidiphila bryophytorum DSM 42138 colonize Arabidopsis thaliana and modulate its proteome
PhytoFrontiers, 2023, (10.1094/PHYTOFR-12-22-0149-R)

F. Bertile, S. Matallana-Surget, A. Tholey, S. Cristobal and J. Armengaud
Diversifying the concept of model organisms in the age of -omics
Commun Biol, 2023, 6, 1062. (10.1038/s42003-023-05458-x)

N. Ramos, D. J. Bigot, G. Zeder-Lutz, J. M. Strub, A. Dagkesamanskaya, R. Fauré, S. Nouaille, C. Y. Montanier, G. Ferry, R. Wagner, S. Cianférani, J. A. Boutin and G. Truan
Genetic Incorporation of Non-canonical Amino Acids in Anti-HER2 VHH: Expression and Characterization
Nanoarchitectonics, 2023, 5 (1), 24-42. (10.37256/nat.5120243482)

A. Declercq, R. Bouwmeester, C. Chiva, E. Sabido, A. Hirschler, C. Carapito, L. Martens, S. Degroeve and R. Gabriels
Updated MS(2)PIP web server supports cutting-edge proteomics applications
Nucleic Acids Res, 2023, (10.1093/nar/gkad335)

M. Chion, C. Carapito and F. Bertrand
Towards a More Accurate Differential Analysis of Multiple Imputed Proteomics Data with mi4limma
Methods Mol Biol, 2023, 2426, 131-140. (10.1007/978-1-0716-1967-4_7)

R. W. Baranowski, J. L. Braun, B. L. Hockey, J. L. Yumol, M. S. Geromella, C. J. F. Watson, N. Kurgan, H. N. Messner, K. C. Whitley, A. J. MacNeil, G. Gauquelin-Koch, F. Bertile, W. Gittings, R. Vandenboom, W. E. Ward and V. A. Fajardo
Toward countering muscle and bone loss with spaceflight: GSK3 as a potential target
Iscience, 2023, 26, ARTN 107047 (10.1016/j.isci.2023.107047)

V. Lehot, P. Neuberg, M. Ripoll, F. Daubeuf, S. Erb, I. Dovgan, S. Ursuegui, S. Cianferani, A. Kichler, G. Chaubet and A. Wagner
Targeted Anticancer Agent with Original Mode of Action Prepared by Supramolecular Assembly of Antibody Oligonucleotide Conjugates and Cationic Nanoparticles
Pharmaceutics, 2023, 15, (10.3390/pharmaceutics15061643)

J. Castel, S. Delaux, O. Hernandez-Alba and S. Cianferani
Recent advances in structural mass spectrometry methods in the context of biosimilarity assessment: from sequence heterogeneities to higher order structures
J Pharm Biomed Anal, 2023, 236, 115696. (10.1016/j.jpba.2023.115696)

G. van Schaick, E. Dominguez-Vega, J. Castel, M. Wuhrer, O. Hernandez-Alba and S. Cianferani
Online Collision-Induced Unfolding of Therapeutic Monoclonal Antibody Glyco-Variants through Direct Hyphenation of Cation Exchange Chromatography with Native Ion Mobility-Mass Spectrometry
Anal Chem, 2023, 95, 3932-3939. (10.1021/acs.analchem.2c03163)

C. Wang, N. Ulryck, L. Herzel, N. Pythoud, N. Kleiber, V. Guerineau, V. Jactel, C. Moritz, M. T. Bohnsack, C. Carapito, D. Touboul, K. E. Bohnsack and M. Graille
N 2-methylguanosine modifications on human tRNAs and snRNA U6 are important for cell proliferation, protein translation and pre-mRNA splicing
Nucleic Acids Res, 2023, (10.1093/nar/gkad487)

C. Sartre, F. Peurois, M. Ley, M. H. Kryszke, W. Zhang, D. Courilleau, R. Fischmeister, Y. Ambroise, M. Zeghouf, S. Cianferani, Y. Ferrandez and J. Cherfils
Membranes prime the RapGEF EPAC1 to transduce cAMP signaling
Nat Commun, 2023, 14, 4157. (10.1038/s41467-023-39894-4)

J. Zumsteg, A. Hirschler, C. Carapito, L. Maurer, C. Villette, D. Heintz, C. Dahl, A. El Nayal, V. Sangal, H. Mahmoud, A. Van Dorsselaer and W. Ismail
Mechanistic insights into sulfur source-driven physiological responses and metabolic reorganization in the fuel-biodesulfurizing IGTS8
Applied and Environmental Microbiology, 2023, ARTN e0082623 (10.1128/aem.00826-23)

Y. Arezki, E. Harmouch, F. Delalande, M. Rapp, C. Schaeffer-Reiss, O. Galli, S. Cianferani, L. Lebeau, F. Pons and C. Ronzani
The interplay between lysosome, protein corona and biological effects of cationic carbon dots: Role of surface charge titratability
Int J Pharm, 2023, 645, 123388. (10.1016/j.ijpharm.2023.123388)

C. I. Butre, V. D’Atri, H. Diemer, O. Colas, E. Wagner, A. Beck, S. Cianferani, D. Guillarme and A. Delobel
Interlaboratory Evaluation of a User-Friendly Benchtop Mass Spectrometer for Multiple-Attribute Monitoring Studies of a Monoclonal Antibody
Molecules, 2023, 28, (10.3390/molecules28062855)

L. Cussonneau, C. Coudy-Gandilhon, C. Deval, G. Chaouki, M. Djelloul-Mazouz, Y. Delorme, J. Hermet, G. Gauquelin-Koch, C. Polge, D. Taillandier, J. Averous, A. Bruhat, C. Jousse, I. Papet, F. Bertile, E. Lefai, P. Fafournoux, A. C. Maurin and L. Combaret
Induction of ATF4-Regulated Atrogenes Is Uncoupled from Muscle Atrophy during Disuse in Halofuginone-Treated Mice and in Hibernating Brown Bears
International Journal of Molecular Sciences, 2023, 24, ARTN 621 (10.3390/ijms24010621)

S. Hessmann, C. Chery, A. S. Sikora, A. Gervais and C. Carapito
Host cell protein quantification workflow using optimized standards combined with data-independent acquisition mass spectrometry
J Pharm Anal, 2023, 13, 494-502. (10.1016/j.jpha.2023.03.009)

V. Piou, C. Vilarem, S. Blanchard, J. M. Strub, F. Bertile, M. Bocquet, K. Arafah, P. Bulet and A. Vétillard
Honey Bee Larval Hemolymph as a Source of Key Nutrients and Proteins Offers a Promising Medium for Artificial Rearing
International Journal of Molecular Sciences, 2023, 24, ARTN 12443 (10.3390/ijms241512443)

C. Brun, C. Allain, P. J. Ferron, H. Younoussa, B. Colicchio, E. Jeandidier, R. M’Kacher, C. Guguen-Guillouzo and F. Bertile
Extended lifespan and improved genome stability in HepaRG-derived cell lines through reprogramming by high-density stress
Proc Natl Acad Sci U S A, 2023, 120, e2219298120. (10.1073/pnas.2219298120)

I. Koutsopetras, A. K. Mishra, R. Benazza, O. Hernandez-Alba, S. Cianferani, G. Chaubet, S. Nicolai and J. Waser
Cysteine-Cysteine Cross-Conjugation of both Peptides and Proteins with a Bifunctional Hypervalent Iodine-Electrophilic Reagent
Chemistry, 2023, e202302689. (10.1002/chem.202302689)

M. Quque, C. Brun, C. Villette, C. Sueur, F. Criscuolo, D. Heintz and F. Bertile
Both age and social environment shape the phenotype of ant workers
Sci Rep, 2023, 13, 186. (10.1038/s41598-022-26515-1)

N. Groysbeck, V. Hanss, M. Donzeau, J. M. Strub, S. Cianferani, D. Spehner, M. Bahri, O. Ersen, M. Eltsov, P. Schultz and G. Zuber
Bioactivated and PEG-Protected Circa 2 nm Gold Nanoparticles for in Cell Labelling and Cryo-Electron Microscopy
Small Methods, 2023, 7, e2300098. (10.1002/smtd.202300098)

E. Desligniere, S. Ollivier, A. Beck, D. Ropartz, H. Rogniaux and S. Cianferani
Benefits and Limitations of High-Resolution Cyclic IM-MS for Conformational Characterization of Native Therapeutic Monoclonal Antibodies
Anal Chem, 2023, 95, 4162-4171. (10.1021/acs.analchem.2c05265)

R. Carapito, R. Li, J. Helms, C. Carapito, S. Gujja, V. Rolli, R. Guimaraes, J. Malagon-Lopez, P. Spinnhirny, A. Lederle, R. Mohseninia, A. Hirschler, L. Muller, P. Bastard, A. Gervais, Q. Zhang, F. Danion, Y. Ruch, M. Schenck, O. Collange, T. N. Chamaraux-Tran, A. Molitor, A. Pichot, A. Bernard, O. Tahar, S. Bibi-Triki, H. G. Wu, N. Paul, S. Mayeur, A. Larnicol, G. Laumond, J. Frappier, S. Schmidt, A. Hanauer, C. Macquin, T. Stemmelen, M. Simons, X. Mariette, O. Hermine, S. Fafi-Kremer, B. Goichot, B. Drenou, K. Kuteifan, J. Pottecher, P. M. Mertes, S. Kailasan, M. J. Aman, E. Pin, P. Nilsson, A. Thomas, A. Viari, D. Sanlaville, F. Schneider, J. Sibilia, P. L. Tharaux, J. L. Casanova, Y. Hansmann, D. Lidar, M. Radosavljevic, J. R. Gulcher, F. Meziani, C. Moog, T. W. Chittenden and S. Bahram
Identification of driver genes for critical forms of COVID-19 in a deeply phenotyped young patient cohort
Science Translational Medicine, 2022, 14, ARTN eabj7521 (10.1126/scitranslmed.abj7521)

F. Fadel, V. Bassim, V. I. Francis, S. L. Porter, T. Botzanowski, P. Legrand, M. M. Perez, Y. Bourne, S. Cianferani and F. Vincent
Insights into the atypical autokinase activity of the Pseudomonas aeruginosa GacS histidine kinase and its interaction with RetS
Structure, 2022, (10.1016/j.str.2022.06.002)

G. Sicoli, A. Konijnenberg, J. Guerin, S. Hessmann, E. Del Nero, O. Hernandez-Alba, S. Lecher, G. Rouaut, L. Mueggenburg, H. Vezin, S. Cianferani, F. Sobott, R. Schneider and F. Jacob-Dubuisson
Large-Scale Conformational Changes of FhaC Provide Insights Into the Two-Partner Secretion Mechanism
Frontiers in Molecular Biosciences, 2022, 9, ARTN 950871 (10.3389/fmolb.2022.950871)

M. Sebastiani, C. Behrens, S. Dorr, H. D. Gerber, R. Benazza, O. Hernandez-Alba, S. Cianferani, G. Klebe, A. Heine and K. Reuter
Structural and Biochemical Investigation of the Heterodimeric Murine tRNA-Guanine Transglycosylase
ACS Chem Biol, 2022, (10.1021/acschembio.2c00368)

T. Rady, L. Turelli, M. Nothisen, E. Tobaldi, S. Erb, F. Thoreau, O. Hernandez-Alba, S. Cianferani, F. Daubeuf, A. Wagner and G. Chaubet
A Novel Family of Acid-Cleavable Linker Based on Cyclic Acetal Motifs for the Production of Antibody-Drug Conjugates with High Potency and Selectivity
Bioconjug Chem, 2022, (10.1021/acs.bioconjchem.2c00314)

V. Poignavent, F. Hoh, G. Terral, Y. Yang, F. X. Gillet, J. H. Kim, F. Allemand, E. Lacombe, C. Brugidou, S. Cianferani, H. Demene and F. Vignols
A flexible and original architecture of two unrelated zinc fingers underlies the role of the multitask P1 in RYMV spread
J Mol Biol, 2022, 167715. (10.1016/j.jmb.2022.167715)

R. Dos Santos Morais, P. E. Santo, M. Ley, C. Schelcher, Y. Abel, L. Plassart, E. Desligniere, M. E. Chagot, M. Quinternet, A. C. F. Paiva, S. Hessmann, N. Morellet, M. F. S. P, F. Vandermoere, E. Bertrand, B. Charpentier, T. M. Bandeiras, C. Plisson-Chastang, C. Verheggen, S. Cianferani and X. Manival
Deciphering cellular and molecular determinants of human DPCD protein in complex with RUVBL1/RUVBL2 AAA-ATPases
J Mol Biol, 2022, 434, 167760. (10.1016/j.jmb.2022.167760)

E. Desligniere, S. Ollivier, A. Ehkirch, A. Martelet, D. Ropartz, N. Lechat, O. Hernandez-Alba, J. M. Menet, S. Clavier, H. Rogniaux, B. Genet and S. Cianferani
Combination of IM-Based Approaches to Unravel the Coexistence of Two Conformers on a Therapeutic Multispecific mAb
Anal Chem, 2022, 94, 7981-7989. (10.1021/acs.analchem.2c00928)

E. Desligniere, H. Diemer, S. Erb, P. Coliat, X. Pivot, A. Detappe, O. Hernandez-Alba and S. Cianferani
A Combination of Native LC-MS Approaches for the Comprehensive Characterization of the Antibody-Drug Conjugate Trastuzumab Deruxtecan
Front Biosci (Landmark Ed), 2022, 27, 290. (10.31083/j.fbl2710290)

A. Declercq, R. Bouwmeester, A. Hirschler, C. Carapito, S. Degroeve, L. Martens and R. Gabriels
MS(2)Rescore: Data-driven rescoring dramatically boosts immunopeptide identification rates
Mol Cell Proteomics, 2022, 100266. (10.1016/j.mcpro.2022.100266)

V. Collin-Faure, B. Dalzon, J. Devcic, H. Diemer, S. Cianferani and T. Rabilloud
Does size matter? A proteomics-informed comparison of the effects of polystyrene beads of different sizes on macrophages
Environmental Science-Nano, 2022, 9, 2827-2840. (10.1039/d2en00214k)

M. Chion, C. Carapito and F. Bertrand
Accounting for multiple imputation-induced variability for differential analysis in mass spectrometry-based label-free quantitative proteomics
PLoS Comput Biol, 2022, 18, e1010420. (10.1371/journal.pcbi.1010420)

J. A. Boutin, J. Stojko, G. Ferry and S. Cianferani
Measuring the NQO2: Melatonin Complex by Native Nano-Electrospray Ionization Mass Spectrometry
Methods Mol Biol, 2022, 2550, 323-328. (10.1007/978-1-0716-2593-4_34)

M. Bobowski-Gerard, C. Boulet, F. P. Zummo, J. Dubois-Chevalier, C. Gheeraert, M. Bou Saleh, J. M. Strub, A. Farce, M. Ploton, L. Guille, J. Vandel, A. Bongiovanni, N. Very, E. Woitrain, A. Deprince, F. Lalloyer, E. Bauge, L. Ferri, L. C. Ntandja-Wandji, A. K. Cotte, C. Grangette, E. Vallez, S. Cianferani, V. Raverdy, R. Caiazzo, V. Gnemmi, E. Leteurtre, B. Pourcet, R. Paumelle, K. Ravnskjaer, G. Lassailly, J. T. Haas, P. Mathurin, F. Pattou, L. Dubuquoy, B. Staels, P. Lefebvre and J. Eeckhoute
Functional genomics uncovers the transcription factor BNC2 as required for myofibroblastic activation in fibrosis
Nat Commun, 2022, 13, 5324. (10.1038/s41467-022-33063-9)

B. Beinsteiner, G. V. Markov, M. Bourguet, A. G. McEwen, S. Erb, A. K. M. Patel, F. Z. El Khaloufi El Khaddar, C. Lecroisey, G. Holzer, K. Essabri, I. Hazemann, A. Hamiche, S. Cianferani, D. Moras, V. Laudet and I. M. L. Billas
A novel nuclear receptor subfamily enlightens the origin of heterodimerization
BMC Biol, 2022, 20, 217. (10.1186/s12915-022-01413-0)

A. Beaussart, F. Canonico, H. Mazon, J. Hidalgo, S. Cianferani, H. Le Cordier, A. Kriznik and S. Rahuel-Clermont
Probing the mechanism of the peroxiredoxin decamer interaction with its reductase sulfiredoxin from the single molecule to the solution scale
Nanoscale Horiz, 2022, 7, 515-525. (10.1039/d2nh00037g)

Y. Arezki, F. Delalande, C. Schaeffer-Reiss, S. Cianferani, M. Rapp, L. Lebeau, F. Pons and C. Ronzani
Surface charge influences protein corona, cell uptake and biological effects of carbon dots
Nanoscale, 2022, (10.1039/d2nr03611h)

S. Awan, M. Lambert, A. Imtiaz, F. Alpy, C. Tomasetto, M. Oulad-Abdelghani, C. Schaeffer, C. Moritz, D. Julien-David, S. Najib, L. O. Martinez, R. L. Matz, X. Collet, R. Silva-Rojas, J. Bohm, J. Herz, J. Terrand and P. Boucher
Wnt5a Promotes Lysosomal Cholesterol Egress and Protects Against Atherosclerosis
Circ Res, 2022, 130, 184-199. (10.1161/CIRCRESAHA.121.318881)

E. Deslignière, O. Hernandez-Alba and S. Cianférani
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